Projects & Publications

Project Age-dependent-Reference-Intervals

Shiny App AdRI

• create Age-dependent Reference Intervals using different methods (LMS, GAMLSS, Window-Methods and Regression)

Shiny App AdRI_GAMLSS

• A visualization tool for continuous reference intervals based on GAMLSS

Shiny App AdRI_rpart

• Automated sex and age partitioning for the estimation of reference intervals using a regression tree model

Shiny App AdRI-Generator

• generating age-dependent analyt-data using functions or given reference intervals

Shiny App Zlog_AdRI

• A zlog-based algorithm and tool for plausibility checks of reference intervals

Shiny App reflimR_Shiny

• A Novel Tool for the Rapid and Transparent Verification of Reference Intervals in Clinical Laboratories

Cooperation on other Shiny Apps

Shiny App for Magnetic Resonance Imaging (MRI) - ShinySurfer

• ShinySurfer: A tool for visualization and statistical analysis of cortical parameters

Shiny App for GenomeNet

• Visualization of state responses of GenomeNet

Packages

NewickReader

• read and print the simple Newick format

reflimR

• reflimR - Reference Limit Estimation Using Routine Laboratory Data
• A Novel Tool for the Rapid and Transparent Verification of Reference Intervals in Clinical Laboratories

Publications

• René Mreches, Alice C. McHardy, Bernd Bischl, Julia Moosbauer, Hüseyin Anil Gündüz, Sandra Klawitter, Zhi-Luo Deng, Eric Franzosa, Curtis Huttenhower, Gary Robertson, Ehsaneddin Asgari, Xiao-Yin To, Martin Binder, & Philipp C. Münch. (2021). GenomeNet/deepG: DeepG pre-release version (v0.1.0-alpha). Zenodo. https://doi.org/10.5281/zenodo.5561229 🧬
• Klawitter, Sandra & Cai, Yixiao & Ye, Baichao & Klawonn, Frank & Sörös, Peter. (2021). ShinySurfer: A tool for visualization and statistical analysis of cortical parameters. 10.7490/f1000research.1118565.1 accepted for OHBM 2021 https://f1000research.com/posters/10-440 🧠
• Klawitter, S., Hoffmann, G., Holdenrieder, S., Kacprowski, T. & Klawonn, F. (2022). A zlog-based algorithm and tool for plausibility checks of reference intervals. Clinical Chemistry and Laboratory Medicine (CCLM). https://doi.org/10.1515/cclm-2022-0688
• Sandra Klawitter, Frank Klawonn und Georg Hoffmann. (2023). Referenzintervalle bei Kindern - Wenn Tabellen an ihre Grenzen stoßen. Trillium Diagnostik (TD) Heft 1/2023. https://doi.org/10.47184/td.2023.01.11
• Klawitter, S. & Kacprowski, T. (2023). A visualization tool for continuous reference intervals based on GAMLSS. Journal of Laboratory Medicine. https://doi.org/10.1515/labmed-2023-0033
• Hoffmann G, Klawitter S, Klawonn F (2024). reflimR: Reference Limit Estimation Using Routine Laboratory Data. R package version 1.0.6, https://CRAN.R-project.org/package=reflimR.
• Hoffmann G, Klawitter S, Trulson I, Adler J, Holdenrieder S, Klawonn F. A Novel Tool for the Rapid and Transparent Verification of Reference Intervals in Clinical Laboratories. Journal of Clinical Medicine. 2024; 13(15):4397. https://doi.org/10.3390/jcm13154397
• Al-Mekhlafi, A., Klawitter, S. & Klawonn, F. (2024). Standardization with zlog values improves exploratory data analysis and machine learning for laboratory data. Journal of Laboratory Medicine. https://doi.org/10.1515/labmed-2024-0051
• Klawitter, S., Böhm, J., Tolios, A. & Gebauer, J. (2024). Automated sex and age partitioning for the estimation of reference intervals using a regression tree model. Journal of Laboratory Medicine. https://doi.org/10.1515/labmed-2024-0083